@bruschi11 https://b12oils.com/rnb.htm
the guys name is Greg. He is a biochemist with 40 year experience.
Here are some of his quotes:
Fix FAD before being able to fix NADPH.. and molybdenum, selenium and iodine have to be those types to build the pathway
5-AR enzymes require NADPH. NADPH needs B1 enzyme to work.
In chronic B2 deficiency you have problems as 3 of the 4 enzymes that use TPP (from thiamine) also require B2 and so in B2 deficiency B1 is lost.
One of the early enzymes in Estrogen synthesis is aromatase., Which is a B2 dependent enzyme
Aromatase requires FAD. For FAD to work it needs B2 and for B2 to work it requires co-factors Iodine, Selenium (sodium selenate), Molybdenum (sodium molybdate)
FAD pathway takes 1-3 months to start working again.
B12 needs B2 to work.
Glutathione needs b2 to work
Ceruloplasmin should work after building FAD pathway
Low cortisol should normalise after fixing fad and b12
Sibo should get better
Etc etc
SIBO:
""As far as gut motility goes, this is basically controlled by 3 things that are vitamin dependent. Histamine, serotonin and Nitric oxide. Histamine production indirectly depends upon B2 levels (and also B6), whilst serotonin depends upon TPH2 status, as well as iron/B2/folate/B12, whilst NO depends upon NOS, which depends upon iron/ B2/folate/B12/B3. If you muck with these then you don't get proper gut motility and this then causes conditions such as IBS and bacterial over-growth.”--©️GRJ
B6 function is dependent on B2, according to GRJ.
"Once you get B12 fixed it should deal with histamine issues, plus it will help mature the gut and it induces a whole bunch of intestinal enzymes that are protective. You can get all sorts of bugs growing when your metabolismis out of whack as you are excreting large amounts of carbon sources and small sugars, which they love to grow on."--GRJ
the guys name is Greg. He is a biochemist with 40 year experience.
Here are some of his quotes:
Fix FAD before being able to fix NADPH.. and molybdenum, selenium and iodine have to be those types to build the pathway
5-AR enzymes require NADPH. NADPH needs B1 enzyme to work.
In chronic B2 deficiency you have problems as 3 of the 4 enzymes that use TPP (from thiamine) also require B2 and so in B2 deficiency B1 is lost.
One of the early enzymes in Estrogen synthesis is aromatase., Which is a B2 dependent enzyme
Aromatase requires FAD. For FAD to work it needs B2 and for B2 to work it requires co-factors Iodine, Selenium (sodium selenate), Molybdenum (sodium molybdate)
FAD pathway takes 1-3 months to start working again.
B12 needs B2 to work.
Glutathione needs b2 to work
Ceruloplasmin should work after building FAD pathway
Low cortisol should normalise after fixing fad and b12
Sibo should get better
Etc etc
SIBO:
""As far as gut motility goes, this is basically controlled by 3 things that are vitamin dependent. Histamine, serotonin and Nitric oxide. Histamine production indirectly depends upon B2 levels (and also B6), whilst serotonin depends upon TPH2 status, as well as iron/B2/folate/B12, whilst NO depends upon NOS, which depends upon iron/ B2/folate/B12/B3. If you muck with these then you don't get proper gut motility and this then causes conditions such as IBS and bacterial over-growth.”--©️GRJ
B6 function is dependent on B2, according to GRJ.
"Once you get B12 fixed it should deal with histamine issues, plus it will help mature the gut and it induces a whole bunch of intestinal enzymes that are protective. You can get all sorts of bugs growing when your metabolismis out of whack as you are excreting large amounts of carbon sources and small sugars, which they love to grow on."--GRJ
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