5 alpha’s new log

Boris

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Oct 3, 2017
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#61
Today’s day four 50MG. I’m getting noticeable results while on it. Very cool. I’m sticking with the potassium. I figure if as of yesterday and today I’m getting results and today will be day three of 300mg potassium why not keep taking it.
Agreed, keep taking potassium not many logs of people doing it with RU in that method
 
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5 alpha

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Oct 3, 2017
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#64
What benefits are you noticing? Any improvement with sexual sides?
Yes I’m four days in and have seen noticeable improvements in these specific sides. Erection quality and with semen quality and quantity. Significant enough improvements that go beyond minor but not 85 percent normal level either. No improvements in sensation and it’s still too early to know if it’s just one of those once in a while feeling somewhat normal things that quickly goes away and has nothing to do with the protocol. But probable is due to protocol. I also continued today with the 3000mg of potassium.

Some stomach aggravation that I contribute to the 30 potassium pills I’m taking but no big deal.
 

brix

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Oct 4, 2017
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#65
Yes I’m four days in and have seen noticeable improvements in these specific sides. Erection quality and with semen quality and quantity. Significant enough improvements that go beyond minor but not 85 percent normal level either. No improvements in sensation and it’s still too early to know if it’s just one of those once in a while feeling somewhat normal things that quickly goes away and has nothing to do with the protocol. But probable is due to protocol. I also continued today with the 3000mg of potassium.

Some stomach aggravation that I contribute to the 30 potassium pills I’m taking but no big deal.
can you not get bulk potassium where you live?
 

Helen

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Oct 5, 2017
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#68
Today’s day four 50MG. I’m getting noticeable results while on it. Very cool. I’m sticking with the potassium. I figure if as of yesterday and today I’m getting results and today will be day three of 300mg potassium why not keep taking it.

Goose ( saw palmetto) is taking just potassium and also feeling improvements.

Potassium increases ACTH, and ACTH DOWNREGULATES AR , but upregulates 5AR and GR.

Sodium downregulates 5AR.

Potassium increases histamine. and acetylcholine.


RU does not touch any AR or ER at these low dosages. Mifepristone - Wikipedia

May be that is why people got worse on higher dosages, which touched AR.


We have troy who was also fast oxidizer with high cortisol and got better from potassium.

Ihatefin, took potassium with histidine and b6 , this increases histamine right before he got better.
 
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5 alpha

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Oct 3, 2017
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#69
Hey mate. Thing is this is like... a long time ago (18-21mo ago?)
So it's hard to recall EXACTLY each thing that has been seized. Funny, I rem mispelling it as ceized yesterday without looking at my post. Anyways.
I think either ella and ru got seized or just one of them, but for sure 2 packages were destroyed, one never heard from again. I think that's it. It was nerve wracking waiting for anything. FOR TEI, I called and debated those health canada pricks. For normal pkgs I still deal with bs here. Socialist controlled state. If I was a fatty or a woman or an ugly homosexual manlet, I'm sure it'd be fine tho.
What websites did you order from
 

5 alpha

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Oct 3, 2017
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#70
Goose ( saw palmetto) is taking just potassium and also feeling improvements.

Potassium increases ACTH, and ACTH DOWNREGULATES AR , but upregulates 5AR and GR.

Sodium downregulates 5AR.

Potassium increases histamine. and acetylcholine.


RU does not touch any AR or ER at these low dosages. Mifepristone - Wikipedia

May be that is why people got worse on higher dosages, which touched AR.


We have troy who was also fast oxidizer with high cortisol and got better from potassium.

Ihatefin, took potassium with histidine and b6 , this increases histamine right before he got better.
If I’m doing better on 50mg than I am on 200mg maybe this is another indicator that my issue is primarily the GR. If this is the case this would suggest the drug is up-regulating my GR receptors resulting in improvement. This is contradictory to my theory that my reaction to cortisol is too strong. At the end of the day though if I continue to do good on 50mg’s of RU and potassium up regulating GR has to be a good thing.
 
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Helen

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Oct 5, 2017
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#71
If I’m doing better on 50mg than I am on 200mg maybe this is another indicator that my issue is primarily the GR. If this is the case this would suggest the drug is up-regulating my GR receptors resulting in improvement. This is contradictory to my theory that my reaction to cortisol is too strong. At the end of the day though if I continue to do good on 50mg’s of RU and potassium up regulating GR has to be a good thing.
You took RU many times. When you take RU the drug is blocking your receptors, it blocks lets say 20% of GR receptors and 20% PR receptor and you experience less action of cortisol. While you are taking RU , it keeps blocking your receptors

and if you read case 1 a) of what I posted its says that you might have problems breaking down cortisol and progesterone since 5AR is closed. and 5AR is what breaksdown cortisol and progesterone.

So as your cortisol and progesterone are higher than needed, this shuts down the LH and the cortisol axis. and you get zero pregnenolone. Thus brain fog no NDMA signaling and no LH.

When you take RU, you basically block the receptors of the hormones which are not broken down. and this opens up the axis, opens up LH< opens up pregnenolone production. and you feel better. It opens up 3 beta hsd, which makes progesterone. So if your progesterone is not broken down then this higher progesterone level closes 3 beta hsd.
When you go off the drug, everything goes back to where it was. since you are not blocking progesterone and cortisol receptors when the drug is out of your system



But in any case I outlined 3 variants in case 1 .

So running ru with potassium is for one of those variants, lets see what happens after you come off. and you are not blocking those receptors



Also there could be a possibility that PR is downregulated. and this then causes closure of 5AR and then cortisol is not broken down. and causing problems. that also could be

.
 
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5 alpha

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5 alpha

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Oct 3, 2017
336
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#72
Today will be my 10th day on 50mg RU. I have decided to extend it to a twelve day run. I’m still also taking the 30mg of potassium. Missed a couple of days on the potassium because it’s messing with my stomach but I still took it yesterday and today and plan on continuing to take it.

I’m still noticeably above what my regular baseline is in all of the symptoms I’m targeting so I would consider this my first successful RU trial since the first one in 2017 that had me feeling 85 percent normal for a few weeks after coming off of it. The difference now is that benefits are not as good and I am getting the benefits on the drug opposed to during a snap back in 2017.

I would take 50mg for thirty days straight if it continued to give me these results but I’m suppose to be getting sedation for a procedure on November 4th so I’ll stop at day twelve so I can get 3-4 days of getting it out of my system before getting sedated with this in my system. Last thing I want to do is tell medical staff I’m on this drug. They will probably commit me haha....

So who knows maybe 50MG of RU combined with potassium could end up being a treatment depending on what case you are. And just keep cycling it. Obviously it would require a large amount of the drug though.
 

Helen

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Oct 5, 2017
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#73
@5 alpha if your progesterone is low , you might not be making NAD. progesterone is there to retain potassium. so if yours is low you cant retain potassium

so if your cant retain potassium and cant make enough progesterone, then your progesterone cant be broken down, and this could be the reason why your 5AR is closed


and this could explain why you are doing better on potassium.

I think you need to test all your hormones at once so you have a clearly picture.


Dont forget, that RU is progesterone, and when you are low on progesterone, and you take RU. RU acts like progesterone. RU blocks progesterone only if progesteone is high, since RU is a weaker progesterone.

so if you take RU plus potassium, it is the same as taking progesterone plus potassium, which retains potassium


So your problem it seems stems from no ability to make progesterone.


You need to test your hormones. all axis, like pregnenolone progesterone. IDO TDO enzymes. that make NAD needed for progesterone production


you see that if you have no potassium then you have low insulin.


and if you have low insulin you make very low NADPH , and thus your steroid axis is closed.


OR your progesterone is too sensitive. and this causes 3 beta hsd closure as a second variant
 
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5 alpha

Well-Known Member
Oct 3, 2017
336
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#74
Today will be my 10th day on 50mg RU. I have decided to extend it to a twelve day run. I’m still also taking the 30mg of potassium. Missed a couple of days on the potassium because it’s messing with my stomach but I still took it yesterday and today and plan on continuing to take it.

I’m still noticeably above what my regular baseline is in all of the symptoms I’m targeting so I would consider this my first successful RU trial since the first one in 2017 that had me feeling 85 percent normal for a few weeks after coming off of it. The difference now is that benefits are not as good and I am getting the benefits on the drug opposed to during a snap back in 2017.

I would take 50mg for thirty days straight if it continued to give me these results but I’m suppose to be getting sedation for a procedure on November 4th so I’ll stop at day twelve so I can get 3-4 days of getting it out of my system before getting sedated with this in my system. Last thing I want to do is tell medical staff I’m on this drug. They will probably commit me haha....

So who knows maybe 50MG of RU combined with potassium could end up being a treatment depending on what case you are. And just keep cycling it. Obviously it would require a large amount of the drug though.
Correction. Today is my ninth day on RU. This Wednesday will make twelve days.
 

5 alpha

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Oct 3, 2017
336
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#75
You took RU many times. When you take RU the drug is blocking your receptors, it blocks lets say 20% of GR receptors and 20% PR receptor and you experience less action of cortisol. While you are taking RU , it keeps blocking your receptors

and if you read case 1 a) of what I posted its says that you might have problems breaking down cortisol and progesterone since 5AR is closed. and 5AR is what breaksdown cortisol and progesterone.

So as your cortisol and progesterone are higher than needed, this shuts down the LH and the cortisol axis. and you get zero pregnenolone. Thus brain fog no NDMA signaling and no LH.

When you take RU, you basically block the receptors of the hormones which are not broken down. and this opens up the axis, opens up LH< opens up pregnenolone production. and you feel better. It opens up 3 beta hsd, which makes progesterone. So if your progesterone is not broken down then this higher progesterone level closes 3 beta hsd.
When you go off the drug, everything goes back to where it was. since you are not blocking progesterone and cortisol receptors when the drug is out of your system



But in any case I outlined 3 variants in case 1 .

So running ru with potassium is for one of those variants, lets see what happens after you come off. and you are not blocking those receptors



Also there could be a possibility that PR is downregulated. and this then causes closure of 5AR and then cortisol is not broken down. and causing problems. that also could be

.
Interesting. I had flagged low androstenedione on a lab report from back in 2014. This would be an indication that my 3 beta HSD is closed right?
 

5 alpha

Well-Known Member
Oct 3, 2017
336
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#76
@5 alpha if your progesterone is low , you might not be making NAD. progesterone is there to retain potassium. so if yours is low you cant retain potassium

so if your cant retain potassium and cant make enough progesterone, then your progesterone cant be broken down, and this could be the reason why your 5AR is closed


and this could explain why you are doing better on potassium.

I think you need to test all your hormones at once so you have a clearly picture.


Dont forget, that RU is progesterone, and when you are low on progesterone, and you take RU. RU acts like progesterone. RU blocks progesterone only if progesteone is high, since RU is a weaker progesterone.

so if you take RU plus potassium, it is the same as taking progesterone plus potassium, which retains potassium


So your problem it seems stems from no ability to make progesterone.


You need to test your hormones. all axis, like pregnenolone progesterone. IDO TDO enzymes. that make NAD needed for progesterone production


you see that if you have no potassium then you have low insulin.


and if you have low insulin you make very low NADPH , and thus your steroid axis is closed.


OR your progesterone is too sensitive. and this causes 3 beta hsd closure as a second variant

Interesting. An explanation as to why It’s possible to have low progesterone levels while inability of progesterone breaking down closing 5AR. It makes sense. If you are not making enough progesterone how could enough be getting broken down.

Your point about RU acting like progesterone if my progesterone is low when I take RU makes it sound like I could also get benefits from progesterone cycles. If increasing progesterone and retaining potassium ends up being my main goal it’s good to know that I can do this by taking progesterone and potassium which sounds more ideal than taking RU.

Is it possible to get your NADPH or NAD tested?

Low insulin would mean my blood sugar would be high or at least in the higher end right? When I first crashed I had low blood sugar readings.

Getting recent full hormone lab test done is something I want to do. After coming off of this run of RU and potassium I really should. Money is tight though. I would have to go argue with endo’s and try to get one to order my labs for me so my insurance would pay for it. My track record with getting doctors to do what I want is not good though.

I will have to research IDO TDO enzymes that make NAD so I can see if it’s possible to get this tested anywhere.

Really what I need is an endo who agrees to do labs for me and hands me the lab order and says “hand this to the lab” than I have a pen and add on what ever I want walking from the docs office to the lab. I have done this twice before and it works. All of the lab tests the ones the doctor wrote on their and the ones I wrote on their got tested and went through the insurance. But the second time I did this the doctor noticed additional tests got done that he did not order and sent me a letter banning me from his practice. So this comes with some risk. I may have to try this again though. Biggest problem is it only works if the doctor hands the patient the lab order before getting your blood drawn.

If the doc does not hand the patient the lab order I suppose you could ask the staff in the lab taking your blood to see it to make sure your info is correct. But you would not be able to write on it right in front of them. You would have to create a decoy somehow and add on what you want. I’m going to need to get creative with this.
 

5 alpha

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Oct 3, 2017
336
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#77
So decided to make yesterday my last day of this run. I was shooting for 10 originally, later thought I would go to twelve but decided to stop at nine.

The last two days I have not been feeling the noticeable improvement. I could keep going with the 50mg of RU plus 3000mg of potassium and hope it comes back. But with PFS it’s usually never that easy. So I’m going to keep my body guessing and stop for a little while, start herb cycling just to see how I react now to a little boost in testosterone and than jump right back on the Mifepristone/potassium cycle in about another ten days
 
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5 alpha

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Oct 3, 2017
336
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#78
So decided to make yesterday my last day of this run. I was shooting for 10 originally, later thought I would go to twelve but decided to stop at nine.

The last two days I have not been feeling the noticeable improvement. I could keep going with the 50mg of RU plus 3000mg of potassium and hope it comes back. But with PFS it’s usually never that easy. So I’m going to keep my body guessing and stop for a little while, start herb cycling just to see how I react now to a little boost in testosterone and than jump right back on the Mifepristone/potassium cycle in about another ten days

So I am 4 days off of the RU/potassium cycle. A majority of the results I got while on it faded. So this is pretty consistent with what Helen said would happen when I came off. The good news is for seven of those nine days I had noticeable improvements in the most stubborn of side effects. So this still tells me that one way or the other RU is the answer for me. This was my second time in the last nine years after taking something or doing anything that actually made me feel somewhat recovered. Everything else for me is just strengthening another area that helps your over all health and situation.

I was on the 50mg of RU for 9 days and for seven of those days I also took 3000MG of potassium.

For my next cycle I’m going to just run potassium at 3000MG per day for let’s say ten days and see what happens. I’ll follow that by just running RU again at 50MG for let’s say 10 days. This way I can get a better idea as to what the potassium is doing.

For the last 4 days I have been taking Tongkat Aki for a nice 4-5 day little Tongkat run to get a little boost in testosterone before it loses it effect at which point I’ll go into herb cycling. Like most PFS veterans I can go by feel to tell what’s happening. I likely got a bump in T despite it doing absolutely nothing for the sexual sides. This is why I’m turned off by any protocol involving taking testosterone or HCG.

I’m sure with pretty much an unlimited amount of RU more ideas along the way will come up with what it can be combined with. I see RU/R-andro and RU/progesterone cycles in the future.
 
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5 alpha

Well-Known Member
Oct 3, 2017
336
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#79
So I am 4 days off of the RU/potassium cycle. A majority of the results I got while on it faded. So this is pretty consistent with what Helen said would happen when I came off. The good news is for seven of those nine days I had noticeable improvements in the most stubborn of side effects. So this still tells me that one way or the other RU is the answer for me. This was my second time in the last nine years after taking something or doing anything that actually made me feel somewhat recovered. Everything else for me is just strengthening another area that helps your over all health and situation.

I was on the 50mg of RU for 9 days and for seven of those days I also took 3000MG of potassium.

For my next cycle I’m going to just run potassium at 3000MG per day for let’s say ten days and see what happens. I’ll follow that by just running RU again at 50MG for let’s say 10 days. This way I can get a better idea as to what the potassium is doing.

For the last 4 days I have been taking Tongkat Aki for a nice 4-5 day little Tongkat run to get a little boost in testosterone before it loses it effect at which point I’ll go into herb cycling. Like most PFS veterans I can go by feel to tell what’s happening. I likely got a bump in T despite it doing absolutely nothing for the sexual sides. This is why I’m turned off by any protocol involving taking testosterone or HCG.

I’m sure with pretty much an unlimited amount of RU more ideas along the way will come up with what it can be combined with. I see RU/R-andro and RU/progesterone cycles in the future.
Today is day seven off of RU and potassium. I’m back to baseline.

I’m going to start a 7-10 day 3000mg of solo potassium run to see what happened’s. I need to know if I will be including potassium with future runs of RU and it seems harmless enough so why not. Either going to start today or wait until tomorrow just to have seven full days off.
 

Olski69

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May 11, 2018
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#80
So I am 4 days off of the RU/potassium cycle. A majority of the results I got while on it faded. So this is pretty consistent with what Helen said would happen when I came off. The good news is for seven of those nine days I had noticeable improvements in the most stubborn of side effects. So this still tells me that one way or the other RU is the answer for me. This was my second time in the last nine years after taking something or doing anything that actually made me feel somewhat recovered. Everything else for me is just strengthening another area that helps your over all health and situation.

I was on the 50mg of RU for 9 days and for seven of those days I also took 3000MG of potassium.

For my next cycle I’m going to just run potassium at 3000MG per day for let’s say ten days and see what happens. I’ll follow that by just running RU again at 50MG for let’s say 10 days. This way I can get a better idea as to what the potassium is doing.

For the last 4 days I have been taking Tongkat Aki for a nice 4-5 day little Tongkat run to get a little boost in testosterone before it loses it effect at which point I’ll go into herb cycling. Like most PFS veterans I can go by feel to tell what’s happening. I likely got a bump in T despite it doing absolutely nothing for the sexual sides. This is why I’m turned off by any protocol involving taking testosterone or HCG.

I’m sure with pretty much an unlimited amount of RU more ideas along the way will come up with what it can be combined with. I see RU/R-andro and RU/progesterone cycles in the future.

I would avoid taking testosterone or HCG. It originally helped me but seemed to lose effectiveness. It did help with some strength in erections etc but for mental sides it was horrible, it was just too much of a roller coaster. It seemed to cause extreme anxiety and panic for me even with ''perfect'' blood ratios.